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Bentham’s Current Alzheimer Research acclaimed in North America

Bussum, Netherlands, 12 February 2010: Current Alzheimer Research recently received appreciation by The Vancouver Sun and the news section published by Temple University. The reports hailed recent research articles published in the journal.

The Vancouver Sun, a Canadian periodical stated that the research published in the current issue of ‘Current Alzheimer Research’ entitled “Effect of Synthetic Cannabinoid HU210 on Memory Deficits and Neuropathology in Alzheimer’s Disease Mouse Model” is a breakthrough study in AD research and will help redirect the future research to more promising therapeutics. The new study, led by Dr. Weihong Song, Canada Research Chair in Alzheimer’s Disease and a professor of psychiatry in the UBC Faculty of Medicine, was the first to test those findings using mice carrying human genetic mutations that cause Alzheimer’s disease – widely considered to be a more accurate model for the disease in humans. “Our study shows that HU210 has no biological or behavioral effect on the established Alzheimer’s disease model,” says Song. “More studies should be done before we place much hope in marijuana’s benefits for Alzheimer’s patients.”

Temple University reported the article entitled “Diet-induced hyperhomocysteinemia increases Amyloid-β formation and deposition in a mouse model of Alzheimer’s disease” published in Vol. 7, No. 2, March 2010 issue of ‘Current Alzheimer Research’ which has opened a new horizon for exploring new strategies for the treatment of Alzheimer disease. Domenico Praticò, PhD, an associate professor of pharmacology in the School of Medicine and the writer of this article said, “When methionine reaches too high a level, our body tries to protect itself by transforming it into a particular amino acid called homocysteine”. A diet rich in methionine, an amino acid typically found in red meats, fish, beans, eggs, garlic, lentils, onions, yogurt and seeds, can possibly increase the risk of developing Alzheimer’s disease. “The data from previous studies show — even in humans — when the level of homocysteine in the blood is high, there is a higher risk of developing dementia. We hypothesized that high levels of homocysteine in an animal model of Alzheimer’s would accelerate the disease.” added Dr. Praticò

'Current Alzheimer Research' (CAR) publishes peer-reviewed frontier review and research articles on all areas of Alzheimer’s disease. The Journal has an impressive impact factor of 4.13 assigned by Journal Citation Reports (JCR, 2008). CAR is listed in PubMed/MEDLINE, Alzheimer Research Forum, Chemical Abstracts, Current Contents, Genamics JournalSeek and PsycINFO databases, and Thomson Scientific products and services, such as 'Science Citation Index Expanded' (also known as SciSearch®),'Neuroscience Citation Index®', 'Journal Citation Reports/Science Edition®', 'BIOSIS Previews' and 'BIOSIS Reviews Reports and Meetings'. To know more about this journal visit www.bentham.org/car. The journal is published by Bentham Science Publishers, the publisher of 92 other print and online journals.











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