Current Cancer Therapy Reviews

ISSN: 1573-3947 - Volume 4, 4 Issues, 2008

Editor-in-Chief:

Allan Lipton
Division of Onology - Room C6830
The Milton S. Hershey Medical Center
Pennsylvannia state University
500 University Drive
Hershey, PA 17033
USA
Tel: 717-531-5960
Fax: 717-531-5076
E-mail: alipton@psu.edu

Editorial Advisory Board:

N. Aaronson (The Netherlands Cancer Institute, Amsterdam, The Netherlands)
R.J. Ablin (University of Arizona College of Medicine, Arizona, USA)
A.A. Adjei (Mayo Clinic, Rochester, MN, USA)
P. Allavena (Istituto Clinico Humanitas, Rozzano, Italy)
A. Almasan (Cleveland Clin. Fdn. Lerner Res. Inst., Cleveland, OH, USA)
C.B. Ambrosone (Roswell Park Cancer Institute, Buffalo, NY, USA)
C.J. Anderson (Washington Univ. Sch. Med., St. Louis, MO, USA)
D. Assimakopoulos (Univ. Ioannina Sch. Med., Ioannina, Greece)
V.I. Avramis (USC Keck Sch. Med., Los Angeles, CA, USA)
F. Balkwill (Barts & London Queen Mary's Sch. Med. & Dent., London, UK)
M. Bar-Eli (Univ. Texas M. D. Anderson Canc. Ctr., TX, USA)
R.C. Bast Jr. (Univ. Texas M. D. Anderson Canc. Ctr., TX, USA)
E.E. Baulieu (INSERM U488, Le Kremlin Bicetre, France)
J.H. Beijnen (Netherlands Cancer Institute, Amsterdam, The Netherlands)
J. Bergh (Karolinska Hosp. & Inst. Radiumhemmet, Stockholm, Sweden)
I.D. Bernstein (Fred Hutchinson Canc. Res. Ctr., Seattle, WA, USA)
J.R. Bertino (UMDNJ-Robert Wood Johnson Med. Sch., New Brunswick, NJ, USA)
M.V. Blagosklonny (New York Medical College, Hawthorne, NY, USA)
H. Bleiberg (Inst. Jules Bordet, Brussels, Belgium)
B. Bonavida (UCLA School of Medicine, Los Angeles, CA, USA)
E. Bouffet (Hosp. Sick Children, Toronto, ON, Canada)
P. Bradley (Queens Medical Centre, University Hospital, Nottingham, UK)
R.H. Brakenhoff (Free University of Amsterdam, Amsterdam, The Netherlands)
M.G. Brattain (Roswell Park Cancer Institute, Buffalo, NY, USA)
L.D. Broemeling (Univ. Texas MD Anderson Canc. Ctr., TX, USA)
D.J. Buchsbaum (Univ. of Alabama at Birmingham, Birmingham, AL, USA)
R.M. Bukowski (Cleveland Clinic Taussig Canc. Ctr., Cleveland, OH, USA)
A.U. Buzdar (Univ. Texas MD Anderson Canc. Ctr., TX, USA)
A. Carbone (Centro di Riferimento Oncologico, Aviano, Italy)
M. Carbone (Loyola Univ. Cardinal Bernardin Canc. Ctr., Maywood, IL, USA)
J. Carlsson (Uppsala University, Uppsala, Sweden)
G. Carruba (ARNAS-Civico, Palermo, Italy)
W. Carson (Ohio State University, Columbus, OH, USA)
N. Cascinelli (Istituto Nazionale, Milan, Italy)
W.K. Cavenee (University of California at San Diego, La Jolla, CA, USA)
P. Chandra (Klinikum der Universitat, Frankfurt, Germany)
P.B. Chapman (Memorial Sloan-Kettering Cancer Ctr., New York, NY, USA)
E. Chu (Yale Univ. Sch. Med., West Haven, CT, USA)
M.A. Chung (RI Hospital, Providence, RI, USA)
F. Ciardiello (Second University of Naples, Naples, Italy)
R. Clarke (Georgetown Univ. Sch. Med., Washington, DC, USA)
G. Clayman (Univ. Texas MD Anderson Canc. Ctr., Houston, TX, USA)
V.P. Collins (Addenbrooke's Hospital, Cambridge, UK)
K.A. Cooney (Univ. Michigan Med. Sch., Ann Arbor, MI, USA)
H. Cortes-Funes (Med. Oncol. Serv. Hosp. Univ. 12 de Octubre, Madrid, Spain)
M. D Incalci (Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy)
W.S. Dalton (Univ. S Florida H Lee Moffitt Canc. Ctr., Tampa, FL, USA)
J.M. Daly (Temple Univ. Sch. Med., Philadelphia, PA, USA)
P.V. Danenberg (USC School of Medicine, Los Angeles, CA, USA)
D.N. Danforth Jr. (National Cancer Institute, NIH, Bethesda, MD, USA)
C.V. Dang (Johns Hopkins Univ. Sch. Med., Baltimore, MD, USA)
A.J. Dannenberg (Cornell Univ. Weill Med. Coll., New York, NY, USA)
S.J. Day (John Wayne Canc. Inst., Santa Monica CA, USA)
A. Deisseroth (Sidney Kimmel Cancer Center, San Diego, CA, USA)
W. Den Otter (Univ. Utrecht BCH, Utrecht, The Netherlands)
M. Detmar (Massachusetts Gen. Hosp., Boston, MA, USA)
E.P. Diamandis (Mount Sinai Hospital, Toronto, ON, Canada)
R.O. Dillman (Hoag Canc. Ctr., Newport Beach, CA, USA)
C. Dittrich (Ludwig Boltzmann-Inst. for Appl. Can. Res., Vienna, Austria)
A. Dowlati (Case Comprehensive Cancer Center, Cleveland, OH, USA)
L. Dubeau (USC Keck Sch. Med., Los Angeles, CA, USA)
W.S. El-Deiry (University of Pennsylvania, Philadelphia, PA, USA)
L.M. Ellis (Univ. Texas MD Anderson Canc. Ctr., Houston, TX, USA)
I.S. Fentiman (Guys Hosp. Hedley Atkins, London, UK)
S. Ferrone (Roswell Park Cancer Institute, Buffalo, NY, USA)
I.J. Fidler (Univ. Texas MD Anderson Canc. Ctr., Houston, TX, USA)
W.D. Figg (National Cancer Institute, NIH, Bethesda, MD, USA)
P.B. Fisher (Columbia Univ. Coll. Phys. & Surg., New York, NY, USA)
R.J. Fitzgibbons (Creighton University Medical Center, Omaha, NE, USA)
J.M. Ford (Stanford Univ. Sch. Med., Stanford, CA, USA)
D.A. Frank (Harvard Medical School, Boston, MA, USA)
A.E. Frankel (Wake Forest Univ. Sch. Med., Winston Salem, NC, USA)
R.S. Freedman (Univ. Texas MD Anderson Canc. Ctr., Houston, TX, USA)
H.S. Friedman (Duke Univ. Med. Ctr., Durham, NC, USA)
H. Fujiki (Tokushima Bunri University, Tokushima, Japan)
S. Fuqua (Baylor Coll. Med., Houston, TX, USA)
N.E. Fusenig (DKFZ-German Cancer Research Center, Heidelberg, Germany)
G. Gabbiani (Univ. Geneva, Geneva, Switzerland)
D.K. Gaffney (University of Utah, Salt Lake City, UT, USA)
G.E. Gallick (Univ. Texas MD Anderson Canc. Ctr., Houston, TX, USA)
B. Gansbacher (Technical University Munich, Munich, Germany)
E. Garattini (Mario Negri Inst., Milan, Italy)
S. Garattini (Mario Negri Inst. Pharmacol. Res., Milan, Italy)
S. Garbisa (University of Padova, Padua, Italy)
G. Gasparini (Azienda Complesso Ospedaliero San Filippo Neri, Rome, Italy)
A.F. Gazdar (Univ. Texas SW Med. Ctr., Dallas, TX, USA)
K. Geboes (University Hospital KUL, Leuven, Belgium)
S.L. Gerson (Case Western Reserve Univ., Cleveland, OH, USA)
A.J. Giaccia (Stanford University, Stanford, CA, USA)
L. Gianni (Istituto Nazionale dei Tumori, Milan, Italy)
R. Giavazzi (Mario Negri Inst. Pharmacol Res., Bergamo, Italy)
T.D. Gilmore (Boston University, Boston, MA, USA)
O. Gimm (Univ. Halle Wittenberg, Halle Saale, Germany)
A. Giordano (Temple University, Philadelphia, PA, USA)
M.J. Glennie (Southampton Gen. Hosp., Hants, UK)
A.K. Godwin (Fox Chase Canc. Ctr., Philadelphia, PA, USA)
D.M. Goldenberg (Garden State Cancer Center, Belleville, NJ, USA)
S. Grant (Virginia Commonwealth Univ. Med. Coll., Richmond, VA, USA)
J.W. Gratama (Erasmus Cancer Center, Rotterdam, The Netherlands)
W.E. Grizzle (University of Alabama at Birmingham, Birmingham, AL, USA)
J.A. Gustafsson (Karolinska Institutet, Huddinge, Sweden)
D.H. Gutmann (Washington Univ. Sch. Med., St. Louis, MO, USA)
K. Haustermans (University Hospital Gasthuisberg, Leuven, Belgium)
R. Hawkins (Univ. Manchester, Manchester, UK)
C.H. Heldin (Ludwig Institute for Cancer Research, Uppsala, Sweden)
I. Hellstrom (University of Washington, Seattle, WA, USA)
D. Herlyn (The Wistar Institute, Philadelphia, PA, USA)
M. Hidalgo (Johns Hopkins Univ. Sch. Med., Baltimore, MD, USA)
E. Hiyama (Hiroshima University, Hiroshim, Japan)
A.N. Houghton (Memorial Sloan-Kettering Cancer Center, New York, NY, USA)
M.M. Hudson (St. Jude Children's Research Hospital, Memphis, TN, USA)
M. Hung (Univ. Texas MD Anderson Canc. Ctr., Houston, TX, USA)
D. Ilson (Memorial Sloan-Kettering Cancer Center, New York, NY, USA)
J.P. Issa (Univ. Texas MD Anderson Canc. Ctr., Houston, TX, USA)
Y. Ito (Kuma Hospital, Kobe, Japan)
E.M. Jaffee (Johns Hopkins Univ. Sch. Med., Baltimore, MD, USA)
J. Jassem (Medical University of Gdansk, Gdansk, Poland)
K.T. Jeang (NIH, Bethesda, MD, USA)
D.H. Johnson (Vanderbilt-Ingram Cancer Center, Nashville, TN, USA)
F.F. Kadlubar (University of Arkansas, Little Rock, AR, USA)
B. Kaina (University of Mainz, Mainz, Germany)
R. Kalluri (Harvard Univ. Sch. Med., Boston, MA, USA)
S. Kaye (The Royal Marsden Hospital, Surrey, UK)
L. Kelland (St. George Hosp. Sch. Med. Antisoma Res. Lab., London, UK)
K. Khalili (Temple University, Philadelphia, PA, USA)
D. Khayat (Salpetriere Hosp., Paris, France)
D.G. Kieback (Baylor Coll. Med. Faculty Center, Houston, TX, USA)
T.J. Kinsella (Univ. Hosp Cleveland, Cleveland, OH, USA)
U.R. Kleeberg (Hämatologisch-Onkologische Praxis Altona, Hamburg, Germany)
G. Kroemer (Institut Gustave Roussy, Villejuif, France)
R. Kurzrock (Univ. Texas MD Anderson Canc. Ctr., Houston, TX, USA)
J.C. Lacal (Instituto de Investigaciones Biomédicas, Madrid, Spain)
S.M. Lippman (Univ. Texas MD Anderson Canc. Ctr., Houston, TX, USA)
G. Lopez-Berestein (Univ. Texas MD Anderson Canc. Ctr., Houston, TX, USA)
E. Lundgren (Umea University, Umea, Sweden)
J. Lunec (Univ. Newcastle upon Tyne, Newcastle upon Tyne, UK)
G.H. Lyman (Univ. Rochester Med. Ctr., Rochester, NY, USA)
H.T. Lynch (Creighton University Sch. Med., Omaha, NE, USA)
L.H. Malkas (Indiana Univ. Sch. Med., Indianapolis, IN, USA)
D. Malkin (Hosp. Sick Children, Toronto, ON, Canada)
A. Manni (Penn State University, Hershey, PA, USA)
L. Mao (Univ. Texas MD Anderson Canc. Ctr., Houston, TX, USA)
F.M. Marincola (Clinical Center, NIH, Bethesda, MD, USA)
J.D. Marks (Univ. Calif. San Francisco General Hospital, San Francisco, CA, USA)
M.J. Mckeage (University of Auckland, Auckland, New Zealand)
C.J. Melief (Leiden University, Leiden, The Netherlands)
H. Mellstedt (Karolinska University Hospital Solna, Stockholm, Sweden)
W.M. Mendenhall (Univ. Florida Coll. Med., Gainesville, FL, USA)
S. Merajver (Univ. Michigan Sch. Med., Ann Arbor, MI, USA)
R. Meredith (Univ. Alabama Med. Ctr., Birmingham, AL, USA)
E. Mihich (Roswell Park Cancer Institute, Buffalo, NY, USA)
L. Milas (Univ. Texas MD Anderson Canc. Ctr., Houston, TX, USA)
S. Monfardini (Azienda Osped University, Padua, Italy)
M. Moore (Memorial Sloan-Kettering Cancer Center, New York, NY, USA)
P.J. Morin (National Institute on Aging, NIH, Baltimore, MD, USA)
F.M. Muggia (NYU School of Medicine, New York, NY, USA)
H. Mukhtar (Univ. Wisconsin, Madison, WI, USA)
R. Narayanan (Florida Atlantic University, Boca Raton, FL, USA)
B.J. Nickoloff (Loyola University of Chicago Med. Ctr., Maywood, IL, USA)
G.L. Nicolson (The Institute for Molecular Medicine, Huntington Beach, CA, USA)
S. Nishimura (University of Tsukuba,Tsukuba, Ibaraki, Japan)
V. Notario (Georgetown Univ. Med. Ctr., Washington, DC, USA)
R.F. Ozols (Fox Chase Cancer Center, Philadelphia, PA, USA)
M. Pagano (NYU School of Medicine, New York, NY, USA)
K. Pantel (Univ. Klinikum Hamburg, Hamburg, Germany)
M. Park (McGill Univ. Hlth. Ctr., Montreal, QC, Canada)
C.D. Pasqualini (Inst. de Invest. Hemat., Buenos Aires, Argentina)
H.I. Pass (NYU School of Medicine and NCI Cancer Center, New York , NY, USA)
S. Pathak (Univ. Texas MD Anderson Canc. Ctr., Houston, TX, USA)
N.A. Pavlidis (Univ. Ioannina Hosp., Ioannina, Greece)
N. Pearce (Massey University, Wellington, New Zealand)
L.J. Penn (Princess Margaret Hosp. Ontario Canc. Inst., Toronto, ON, Canada)
C.A. Perez (Washington Univ. Sch. Med., St. Louis, MO, USA)
R.G. Pestell (Georgetown Univ. Lombardi Comp. Canc. Ctr., Washington, DC, USA)
S. Pestka (Robert Wood Johnson Med. Sch., Piscataway, NJ, USA)
D. Phillips (Institute of Cancer Research, Surrey, UK)
S. Phuphanich (Winship Cancer Inst. Emory Univ., Atlanta, GA, USA)
M. Pierotti (Istituto Nazionale Tumori, Milan, Italy)
M. Pignatelli (Univ. Bristol Sch. Med., Bristol, UK)
Y.G. Pommier (National Cancer Institute, NIH, Bethesda, MD, USA)
G. Powis (University of Arizona, Tucson, AZ, USA)
G.C. Prendergast (Thomas Jefferson University, Wynnewood, PA, USA)
J.J. Rafter (Karolinska Institutet, Huddinge, Sweden)
M.F. Rajewsky (University of Essen Medical School, Essen, Germany)
M.J. Ratain (Univ. Chicago Canc. Res. Ctr., Chicago, IL, USA)
A. Ravaud (Hôpital Saint Andre, Bordeaux, France)
A. Raz (Wayne State Univ. Sch. Med., Detroit, MI, USA)
G.H. Reaman (Childrens Natl. Med. Ctr., Washington, DC, USA)
R. Rees (Nottingham Trent University, Nottingham, UK)
R.A. Reisfeld (Scripps Res. Inst., La Jolla, CA, USA)
J. Ritz (Dana Farber Canc. Inst. Harvard Med. Sch., Boston, MA, USA)
P.D. Robbins (Univ. Pittsburgh Sch. Med., Pittsburgh, PA, USA)
D.J. Robbins (Dartmouth Medical School, Hanover, NH, USA)
J. Robert (Inst. Bergonie, Bordeaux, France)
J.A. Roth (Univ. Texas MD Anderson Canc. Ctr., Houston, TX, USA)
E.K. Rowinsky (Inst. Drug Dev. Canc. Therapy & Res. Ctr., San Antonio, TX, USA)
W. Sadee (Ohio State University, Columbus, OH, USA)
P.M. Schlag (Charité Universitätsmedizin Berlin, Berlin, Germany)
J. Schlom (National Cancer Institute, NIH, Bethesda, MD, USA)
M.V. Seiden (Massachusetts Gen. Hosp., Boston, MA, USA)
A.M. Senderowicz (NICDR, NIH, Bethesda, MD, USA)
A.K. Shamsuddin (Univ. Maryland Sch. Med., Baltimore, MD, USA)
G.V. Sherbet (Univ. Newcastle Upon Tyne, Newcastle upon Tyne, UK)
R.M. Simmons (NY Weill Cornell Canc. Ctr. at Cornell Univ., New York, NY, USA)
R. Soffietti (University of Turin, Turin, Italy)
D.A. Spandidos (Univ. Crete Sch. Med., Crete, Greece)
E.J. Stanbridge (Univ Calif. Irvine, Irvine, CA, USA)
E.D. Staren (Medical College of Ohio, Toledo, OH, USA)
P.S. Steeg (National Cancer Institute, NIH, Bethesda, MD, USA)
G.S. Stein (Univ. Massachusetts Sch. Med., Worcester, MA, USA)
C.F. Stewart (St. Jude Children's Research Hospital, Memphis, TN, USA)
Y. -J. Surh (Seoul National University, Seoul, South Korea)
E. Tahara (Hiroshima Cancer Seminar Foundation, Hiroshima, Japan)
M.M. Taketo (Kyoto Univ. Grad. Sch. Med., Kyoto, Japan)
C.H. Takimoto (Cancer Therapy and Research Center, San Antonio, TX, USA)
M.S. Tallman (Northwestern Univ. Feinberg Sch. Med., Chicago, IL, USA)
M. Talpaz (Univ. Texas MD Anderson Canc. Ctr., Houston, TX, USA)
H. Tanaka (Nippon Shinyaku Co. Ltd., Kyoto, Japan)
Z.Y. Tang (Fudan University, Shanghai, China)
B.T. Teh (Van Andel Research Institute, Grand Rapids, MI, USA)
B.A. Teicher (Genzyme Corp., Framingham, MA, USA)
K. D. Tew (Medical University of South Carolina, Charleston, SC, USA)
D. Theodorescu (Univ. Virginia Hlth. Sci. Ctr., Charlottesville, VA, USA)
P. Therasse (EORTC, Brussels, Belgium)
C.R. Thomas (OHSU, Portland, OR, USA)
D.J. Tindall (Mayo Medical School, Rochester, MN, USA)
E.L. Travis (Univ. Texas MD Anderson Canc. Ctr., Houston, TX, USA)
E. Van Cutsem (University Hospital Gasthuisberg, Leuven, Belgium)
P. Vaupel (University of Mainz, Mainz, Germany)
C.L. Vecchia (Mario Negri Inst., Milan, Italy)
U. Veronesi (European Institute of Oncology, Milan, Italy)
P.T. Vihko (University of Oulu, Oulu, Finland)
T. Von Zglinicki (Univ. Newcastle, Newcastle upon Tyne, UK)
H.P. Wagner (University of Bern Medical Center, Bern, Switzerland)
T.A. Waldman (Georgetown University Medical Center, Washington, DC, USA )
H. Wallace (Royal Hospital for Sick Children, Edinburgh, UK)
D.K. Watson (Med. Univ. S Carolina Hollings Canc. Ctr., Charleston, SC, USA)
S. Waxman (Mt. Sinai Sch. Med., New York, NY, USA)
R.R. Weichselbaum (The University of Chicago, Chicago, IL, USA)
D.R. Welch (Univ. of Alabama at Birmingham, Birmingham, AL, USA)
T. Whiteside (Univ. Pittsburgh Sch. Med., Pittsburgh, PA, USA)
J. Whitfield (Natl. Res. Council Canada, Ottawa, Canada)
P. Workman (Canc. Res. UK Ctr. Canc. Therapeut. , Surrey, UK)
J. Xiang (Saskatoon Cancer Center, Saskatoon, Canada)
H. Yamasaki (Kwansei Gakuin University, Sanda, Japan)
J.R. Yannelli (Univ. Kentucky Sch. Med., Lexington, KY, USA)
W. Zhang (Univ. Texas MD Anderson Canc. Ctr., Houston, TX, USA)