Medicinal Chemistry

ISSN: 1573-4064 - Volume 4, 6 Issues, 2008

Online Abstract Submission

Instructions for Authors

Manuscripts should be submitted openly to one of the following Editors without prior invitation at the following addresses:

Prof. Atta-ur-Rahman, FRS
Editor, Medicinal Chemistry
H.E.J. Research Institute of Chemistry
University of Karachi
Karachi-75270
Pakistan
Tel: (+92)-21-482-4924 , (+92)-21-482-4925
Fax:(+92)-21-461-2073,(+92)-21-497-7491,(+92)-21-497-5781,(+92)-21-481-9018,(+92)-21-481-9019
E-mail: mc@bentham.org

Dr. William J. Hoekstra

Co-Editor, Medicinal Chemistry
Glaxo SmithKline R & D
5 Moore Drive, NTH-M1107
Research Triangle Park
NC 27709-3398
USA
Tel: (+1)-919-483-8212
E-mail: william.j.hoekstra@gsk.com

Dr. Andreas Hilgeroth

Co-Editor, Medicinal Chemistry
Martin-Luther-Universitaet Halle-Wittenberg
Fach-bereich Pharmazie, Wolfgang-Langenbeck-Str.4
06120 Halle
Germany
Tel: +49-(0)345-55-25168/-25124
E-mail: hilgeroth@pharmazie.uni-halle.de

It is advisable that the authors submit an abstract to the Editor by e-mail, prior to submitting the full manuscript. The submitted abstract should outline the intended contents and coverage of their article. The original article manuscript, written in English, should not exceed 25 journal pages (75 manuscript pages) and it should be typed in double spacing throughout on A-4 or US Letter (8.5x11 inches) paper. Short Communications reporting seminal reports of important findings are also accepted in the journal, and these should be limited to 4 journal pages (12 manuscript pages). Dot matrix print or any print that is difficult to read is unacceptable. Two copies of the manuscript must accompany the original and should be sent to the Editor at his given address. All pages should be numbered. Abbreviations should be defined the first time that they are used in the manuscript and a list of abbreviations used should also be provided. Short Communications are also accepted for publication of preliminary reports of novel significance. Communications should not exceed 4 journal pages (12 double-spaced manuscript pages). The journal also publishes a leading review article in each issue. The Reviews Editor normally solicits review articles, however, prospective authors are encouraged to submit their proposals for reviews by contacting the Reviews Editor Prof. David Fairlie at Email: d.fairlie@imb.uq.edu.au

Manuscript Organization: The manuscript should be divided as: Title page, abstract and the main text. The text may be subdivided further according to the areas to be discussed. After the text follows the Experimental and Reference sections. The first page should contain the title, the authors’ names (initials and surname only), with an asterisk to mark the name of the principal author.

Conflict of Interest: Financial contributions to the work being reported should be clearly acknowledged, as should any potential conflict of interest.

Abstract: The abstract should not exceed 250 words and it should condense the essential features of the article.

Key Words: Authors must supply up to eight key words along with their manuscript.

Text: The main text should begin on a separate page and it may be subdivided into separate sections. The reference numbers should be given in square brackets in the text. Acknowledgements should be kept to a minimum.

Tables:

  • Data Tables should be submitted in Microsoft Excel or in Microsoft Word table format.
  • Each table should include a title/caption explaining what the table shows. Detailed legends may then follow.
  • Tables should be given on separate pages with indications on the left hand margin to the text, as to the appropriate placement of the tables.
  • Tables should not contain vertical rules.
  • Columns and rows of data should be made visibly distinct by ensuring the borders of each cell display as black lines.
  • Tables should be numbered consecutively in order of their citation in the body of the text, with Arabic numerals.
  • If a reference is cited in both the table and text, insert a lettered footnote in the table to refer to the numbered reference in the text.
  • Tabular data provided as additional files can be submitted as an Excel spreadsheet.

Figures / Illustrations:

All authors must strictly follow the guidelines below for preparing illustrations for publication in Medicinal Chemistry. If the figures are found to be sub-standard, then the manuscripts will be rejected/ and the authors offered the option of figure improvement professionally by Bentham Publishing Services. The costs for such improvement will be charged to the authors.

Editorial Requirements:

The quality of the illustrations printed in the journal largely depends on the quality of the figures/illustration provided by the author. The acceptance of a manuscript for publication is subject to the figures being up to the highest standards in terms of clarity and resolution. In case the figures supplied are not up to the standards required, then the manuscripts will be rejected, and the authors given the option to either return the manuscripts within one week with appropriate drawings/figures or they may opt to have these professionally prepared through the paid professional service available from Bentham Publishing Services.

  • Submit the original artwork or a photographic print of the original for publication.
  • Do not submit photocopies. (Hardcopy submission requirement).
  • Illustrations should be provided as separate files, not embedded in the text. (Hardcopy submission requirement).
  • Remove all color from graphics except for those illustrations (Greyscale), which are intended to be printed in color.
  • Good quality of hardcopy originals are a requirement.
  • Figures should be referred to as “Fig. (1)”, “Fig. (2)” etc. in the text with figure numbers in bold within round bracket.
  • Revised manuscripts should contain a complete set of artwork and photographs.

Technical Details:

  • Figures should be provided on high quality, white, smooth opaque paper. (Hardcopy requirement).

Format & Resolution:

  • The following file formats can be accepted. (Preference in order of appearance): PDF, TIFF, JPEG, GIF.
  • Illustrations must fit a single or double column format on the journal page, according to the following guideline below:


HEIGHT
WIDTH
SINGLE COLUMN
24 cm (max)
8.5 cm (max)
DOUBLE COLUMN
24 cm (max)
18 cm (max)

  • Whenever possible, submit graphics that do not have to be reduced to fit the standard figure size.
  • Use the best resolution available (hardcopy submission requirement). For online submission the maximum resolution is 300 dpi.
  • Avoid textures and shadings giving a three-dimensional effect to the illustration.
  • Symbols and lettering in the illustration should be of similar size.
  • Smaller lettering is used.
  • Font: Times New Roman or Helvetica is preferable. Font size: 10pt (maximum).
  • Line drawings should have clear and sharp lines and should be of uniform density. Moreover, lines should be continuous without any breaks.
  • Do not use lines thinner than 1 point.

Color Figures / Illustrations:

  • The cost for the first published page of color figures is US$ 780; the second additional page will be for US$ 570, and each subsequent page for US$ 385.
  • Color figures should be supplied in CMYK not RGB colors.
  • Required resolution for online submission is 300 dpi. In case of hardcopy submission, please use the maximum resolution available. In case the figure(s) are of an inferior quality they will need to be improved either by the author or by the publisher on a charged basis.

Photographs:

Submit high-contrast prints that are of single- or double-column width so that they will not have to be reduced when printed. Negatives are not acceptable. However, in case of hardcopy submission, color illustrations and plates can be published from 35 mm color slides.

Chemical Structures: Chemical structures must be prepared according to the guidelines below.

Structures should be prepared using a suitable drawing program e.g. ChemDraw and provided as separate file, submitted both on disk and in printed formats.

Numbers in bold should identify all chemical structure. If a name is also used to describe the compound, the associated number in bold should be in parenthesis, e.g. “compound (1)”.

Structure Drawing Preferences:

[As according to the ACS style sheet]

Drawing Settings:

Chain angle       120°

Bond spacing    18% of width

Fixed length       14.4 pt (0.500cm, 0.2in)

Bold width          2.0 pt (0.071cm, 0.0278in)

Line width           0.6 pt (0.021cm, 0.0084in)

Margin width       1.6 pt (0.096cm)

Harsh spacing    2.5 pt (0.088cm, 0.0347in)

Text settings:

Font                    Times New Roman / Helvetica

Size                    10pt

Under the Preference Choose:

Units                    points

Tolerances          3 pixels

Under Page Setup Use:

Paper                  US letter

Scale                  100%

Experimental Section: Experimental descriptions must be as concise as possible. The title of an experiment should include the chemical name and compound number and use of chemical formulas and standard abbreviations is encouraged. Sufficient spectral data such as NMR data should be included in the Experimental Section for all new compounds reported. Adequate evidence to establish the degree of purity must be provided for all target compounds. Quantitative biological data are required for all final/target compounds.

References: For the format of references, see the ACS Style Guide, pp 106-114,

Examples:

Journal Reference:
Thomsen, R.; Christensen, M.H. MolDock: a new technique for high-accuracy molecular docking. J. Med. Chem., 2006, 49, 3315-21.

Book Reference:
Rahman, A.-U.; Shah, Z. Stereoselective Synthesis in Organic Chemistry, Springer-Verlag: New York, 1993.

Book Chapter Reference:
Wheeler, D.M.S.; Wheeler, M.M. In Studies in Natural Products Chemistry; Atta-ur-Rahman, Ed.; Elsevier Science B. V: Amsterdam, 1994; Vol. 14, pp. 3-46.

Abstracts, unpublished data and personal communications (which can only be included if the permission has been obtained) should not be given in the reference section but they may be mentioned in the text with details provided as footnotes. All authors of referenced papers must be cited and there must be no use of the short hand version of et al. when citing the authors.

Manuscript Submission: Two copies of the manuscript must accompany the original along with the soft copy of the manuscript on a computer floppy disk(s) in MS Word file format (or created in any other well-known word processing software) should be submitted. To achieve rapid publication authors are encouraged to e-mail or fax their submission to the appropriate editorial office (see above) at the same time that they mail the manuscript. For even faster publication, authors are encouraged to submit their entire manuscript via Bentham’s online submission service (see below). Authors must provide their full address, telephone and fax numbers with e-mail address with all submissions.

For expedient and speedy reviewing of author's manuscripts, authors are strongly advised to include the PDF file of their manuscript on a floppy or zip disk, into the mailing material. At the same time the package is mailed, please also send by e-mail a copy of the PDF file of the manuscript to the editorial office.

Online Manuscript Submission: (preferable)

To facilitate speedy and cost-effective submission of abstracts and manuscripts, an online submission and tracking service via Internet is being offered. Once the Editor-in-Chief of the journal has accepted your abstract, we would prefer that you submit your full manuscript online via our online submission service available at www.bentham-mps.org. For online submission, please provide your complete manuscript in the form of a single zipped folder containing all the material (main text, figures/ illustrations, scanned photographs, tables, chemical structures drawn in ChemDraw) as separate files and a PDF version of the entire manuscript with all the figures/ illustrations / tables / chemical structures etc., embedded in the text exactly in the manner as they should appear in printing. Authors are required to proofread the PDF version of their manuscript before submission. The article will be published exactly as received and the Publishers will not be responsible for any error occurring in the manuscript in this regard.

For online submission of manuscripts, these should be submitted via our online manuscript submission service available at www.bentham-mps.org or by FTP submission at www.bentham-ftp.org

You may, however, still submit your abstracts and manuscripts through conventional surface mail.

A successful electronic submission of a manuscript will be followed by a system-generated acknowledgement to the principal/corresponding author within 72 hours of the dispatch of the manuscript. Any queries therein should be addressed to mahmood@bentham.org and copied to Jalil@bentham.org

Page Charges: No page charges will be levied to authors.

Language Editing: Manuscripts submitted containing many English typographical errors will not be published. Authors from non-English language countries are advised to use the services of our professional language editing department prior to submitting their manuscript to the Journal. Please contact Bentham Publishing Services www.benthampublishingservices.com for a language editing quote at e-mail: info@benthampublishingservices.com stating the total number of words of the article to be edited.

Proofs: Authors are sent page proofs. To avoid delays in publication, proofs should be checked immediately for typographical errors and returned within 48 hours. Authors will be charged for excessive changes made at the page proof stage.

Reprints: Each first-named (corresponding) author will receive electronically a certain number of free reprints. Reprints may be ordered from the Publisher prior to publication of the article. First named authors may also order a personal print and online subscription of the journal at 50% off the normal subscription rate by contacting the subscription department at e-mail: subscriptions@bentham.org

Bentham Open Access: Accepted articles can be published online for free open access for all to view. Open access publishing provides the maximum dissemination of the article to the largest audience. Authors must pay for this service. All corresponding authors will be asked to indicate whether or not they wish to pay to have their paper made freely available on publication. If authors do not select the Open Access option, then their article will be published with standard subscription-based access at no charge.

Bentham Science offers authors the choice of open access publication of their articles at a fee of US$ 2,800 per published article which allows indefinite online publication with BOTH Bentham Science and PubMed Central. For authors who select this option, Bentham Science will undertake to deposit these articles in PubMed Central and to make these freely available on publication.

Alternatively, authors may choose to publish their article with Bentham Science at a reduced fee for a limited open access period. Bentham Science is the first and only publisher to offer authors the choice at a reduced open access fee to have their article published for a limited open access period. For open access publication for a period of twelve months (limited open access) the per article fee is US$ 1,400.

For more information please contact us at e-mail: openaccess@bentham.org

Reviewing and Promptness of Publication: All papers submitted for publication will be immediately subjected to editorial scrutiny, usually in consultation with members of the Editorial Advisory Board. Every effort will be made to assess the papers quickly. The papers will be typeset and the proofs dispatched to the authors normally within 4 weeks of their acceptance.

Copyright: It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously submitted or published elsewhere. Plagiarism is strictly forbidden, and by submitting the article for publication the authors agree that the publishers have the legal right to take appropriate action against the authors, if plagiarism is discovered. By submitting a manuscript the authors agree that the copyright of their article is transferred to the publishers if and when the article is accepted for publication.

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