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Mini-Reviews in Medicinal Chemistry

CONTENTS

Volume 1, Issue 1

 

Molecular Moments for Computer-Aided Drug Discovery

B. D. Silverman*

 

Modifying TNFa for Therapeutic Use: A Perspective on the TNF Receptor System

Akihiro Hasegawa, Watrau Takasaki**, Mark I. Greene and Ramachandran Murali*

 

Recent Advances in Bioreductive Drug Targeting

M. A. Naylor* and P. Thomson

 

DNA Tetraplex-Binding Drugs: Structure-Selective Targeting is Critical for Antitumour Telomerase Inhibition

Philip J. Perry and Terence C. Jenkins*

 

Small Molecule Inhibitors of Serine/Threonine Protein Phosphatases

Adam McCluskey^1* and Jennette A. Sakoff²

 

Nitric Oxide-Releasing Nonsteroidal Anti-inflammatory Drugs: Novel Gastrointestinal-Sparing Drugs

Upul K. Bandarage* and David R. Janero

 

Enterohepatic Recirculation: A Powerful Incentive for Drug Discovery in the Inosine Monophosphate Dehydrogenase Field

Christos Papageorgiou*

 

A Comparison of Methods for Pharmacophore Generation with the Catalyst Software and their Use for 3D-QSAR: Application to a Set of 4-Aminopyridine Thrombin Inhibitors

P.A. Greenidge* and J. Weiser^b

 

Recent Advances in the Development of Dopamine D₃ Receptor Agonists and Antagonists

Michael Crider^†* and Mark A. Scheideler

 

Structure-Metabolism Relationships: Steric Effects and the Enzymatic Hydrolysis of Carboxylic Esters

Peter Buchwald*

 

Structure-Function Relationships in Chloroquine and Related 4-Aminoquinoline Antimalarials

Timothy J. Egan*

 

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