Xiangdong Wang
Dr. Wang is a professor of Medicine at Fudan University,
visiting professor of Clinical Sciences at Lund University,
and adjunct professor of Molecular Biosciences at North
Carolina State University. He also serves as the Senior
Advisor for Chinese Medical Doctor Association and a Director
of National Program of Doctor-Pharmaceutist communication.
Dr Wang has been working on roles of gut epithelial barrier
function, hepatocyte transplantation, pancreatic epithelial
cells, and pulmonary epithelial cells in pathogenesis of
inflammation, organ dysfunction and cancer. He served as
the principle scientist, global disease advisor, regional
medical director and chairman of scientific advisor board
for pharmaceutical companies and research organizations.
His current research focuses on roles of epithelial cells
in development of organ dysfunction and potential interaction
between drugs and epithelial cells.
Antonio Esquinas

Dr. Antonio Esquinas is an Intensivist and staff physician
of Intensive Care Unit Hospital Morales Meseguer. Murcia.
Spain. He is also an Active Member and International Fellow
American Association Respiratory Care (AARC) Fellow American
Collage Chest Physicians. (ACCP).
His research related with non invasive mechanical ventilation
in respiratory care and physiotherapy in critically. His
principal research activities are: Noninvasive mechanical
ventilation, epithelial and physiology changes during
humidification and impact and effect of High frequency
chest wall compression in critically patients undergoing
mechanical ventilation in airway physiology.
He had promoted research activities as coordinator of some
working groups and research activities with Ibero American
Working group of Noninvasive mechanical ventilation, epithelial
changes during Humidification, and airway techniques for
bronquial clearance in critically patients undergoing mechanical
ventilation.
James M. Maguire

Dr. Maguire is currently the Senior Scientist/Lecturer for
Pall Life Sciences.
He is also the Senior Consultant to the Respiratory Care
Department at the Veterans Administration Medical Center/Dartmouth
Alliance, in White River Junction Vermont. He is on the
Board of Directors for The American Association of Respiratory
Care as well as the American College of Chest Physician's
Governor for the State of Vermont. Dr. Maguire is on the
Editorial Board of Several Medical Journals and reviews
for many more. He is a former Consulting Surveyor for the
Joint Commission. Dr. Maguire is also on the Board of Advisors
for California College of Health Sciences and sits on the
International Committee for the AARC. He is currently working
on contamination of patients via contaminated hospital water.
Lorraine J. Gudas

Dr. Gudas is Chairman and Revlon Pharmaceutical Professor
of Pharmacology and Toxicology of the Pharmacology Department
at Weill Cornell Medical College. She is a member of the
American Society for Pharmacology and Experimental Therapeutics,
the major organization of scientists doing research in pharmacology.
She finished a term as an elected member of the Board of
Directors of the American Association of Cancer Research,
the largest organization of cancer researchers in the United
States. Dr. Gudas was also the chair of the Board of Scientific
Counselors of the National Institute of Diabetes and Digestive
and Kidney Disorders until July, 2007, and is on the external
advisory boards of three Cancer Centers: The Vermont Cancer
Center, The Lineberger Cancer Center of U.N.C. Chapel Hill,
and The University of Maryland Greenebaum Cancer Center.
Of note, in 1999, she received the 2nd Annual "Woman
in Cancer Research" award from the American Association
of Cancer Research. She has had a long-standing research
interest in vitamin A and its derivatives and metabolites,
a group of compounds called retinoids. She and her laboratory
have studied the pharmacology and molecular actions of retinoids
with respect to cancer treatment, cancer prevention, and
stem cell differentiation.
Wei Wu

Dr. Wu is a professor and oncologist in the School of Public
Health and Family Medicine at Capital University of Medical
Sciences, P.R.China. He used to an assistant professor in
the Division of Biomedical Sciences at University of California,
Riverside. He also serves as an editorial board member for
Journal of Medical Sciences Research and Scientific Journals
International.
His studies are to investigate the molecular mechanisms
of tumor metastasis. His studies showed that human chorionic
gonadotropin β
(HCG β)
induced tumor migration and invasion, and downregulated
tumor metastasis inhibitor, E-cadherin, in human prostate
cancer DU145 and PC3 cells. He also works on the signaling
pathways of breast cancer and osteosarcoma,etc.
Gary Laverty

Dr. Laverty is an Associate Professor of Biological Sciences
at the University of Delaware. Dr. Laverty studies epithelial
transport processes in intestinal and renal tissue, and
the endocrine regulation of these systems. Current interests
include the regulation of intestinal transport activity
by dietary salt intake and aldosterone, and the effects
of parathryoid hormone on renal proximal tubule acid-base
transport and chloride secretion. A related interest is
in the role of the cystic fibrosis transmembrane regulator
(CFTR) in controlling and organizing epithelial transporters.
A comparative approach is used to investigate many of these
systems.
Wolfgang Sadee

Wolfgang Sadée is Felts Mercer Professor of Medicine
and Pharmacology, Chair, Department of Pharmacology, and
Director, Program in Pharmacogenomics, College of Medicine,
at The Ohio State University, Columbus. He also holds appointments
in Pharmacy, Medical Genetics, and Psychiatry, and is member
of the Davis Heart and Lung Research Institute and the OSU
Comprehensive Cancer Center. He has received a doctorate
in Pharmaceutical Chemistry at the FU Berlin in 1968, and
has served on the pharmacy faculties of USC and UCSF until
2002. Dr. Sadée’s research focuses on pharmacogenomics
relevant to various diseases, drug discovery, and drug addiction,
with over 300 research papers and monographs. He has served
as founding editor of Pharmaceutical Research and The AAPS
Journal, and has received the AAPS Distinguished Scientist
Award.
R. Clark Lantz

R. Clark Lantz, PhD, is Professor and Associate Head of
Cell Biology and Anatomy at the University of Arizona College
of Medicine. He is also the Deputy Director of the Southwest
Environmental Health Science Center, an NIEHS funded Center
of Excellence. Dr. Lantz’s research interests are
in the chronic effects of low dose environmental exposures
on the lung. Recent results from Dr. Lantz’s research
has indicated that arsenic exposure at environmental levels
can alter airway epithelial cell repair processes. Dr. Lantz
is currently the Principal Investigator on an EPA grant
which is determining alterations in airway epithelial cell
proteins following arsenic exposure. He is also currently
investigating the effect of in utero and early postnatal
exposures to arsenic on lung structure and function.
Colin Ockleford

Colin Ockleford is Professor of Anatomy at the Lancaster
University School of Health and Medicine and a visiting
Professor at the University of Leicester where he is Director
of the Laboratory for Developmental Cell Sciences. He was
made a Fellow of the Royal College of Pathologists in recognition
of his work on the human maternofetal interaction and in
particular the morphogenesis of the chorionic villus tree
and receptor mediated transepithelial transport of antibodies.
He has focussed studies on the role of the trophoblastic
and amniotic epithelia in implantation, placentation and
parturition. Most recently he has published on the hypertensive
disease of pregnancy pre-eclampsia and the invasive properties
and blood borne deportation of trophoblast and has researched
the signalling systems regulating these activities as part
of the EMBIC consortium. A winner of the Symington Prize
and the Stevenson Award he has served on a variety of editorial
boards including Journal of Anatomy, Placenta and the European
Journal of Morphology. He chairs the Department of Medicine
Research Committee at Lancaster University, is on the Medical
and Toxicological Panel of the Pesticides Safety Directorate
and a member of the Ministerial Advisory Committee on Pesticides
of the Department of the Environment Food and Rural Affairs.
Naoki Mori

Dr. Mori is a professor of Division of Molecular Virology
and Oncology, Graduate School of Medicine, at University
of the Ryukyus. He also serves on the editorial board of
Retrovirology. Dr Mori has been working on inflammation
induced by human T-cell leukemia virus type 1, dengue virus,
Helicobacter pylori, Pseudomonas aeruginosa,
and Legionella pneumophila in gastric, bronchial,
lung, thyroid, synovial, and hepatic epithelial cells. His
current research focuses on the molecular mechanisms of
host cell signal transduction and subsequent activation
of epithelial cells by pathogens and their virulence factors.
Recently, he develops new therapeutic strategies by which
targeted inhibition of selected signaling pathway components.
Samuel C. Mok
Dr. Mok is a professor of the Department of Gynecologic
Oncology at the University of Texas M.D. Anderson Cancer
Center. Dr Mok has been working on projects related to the
delineation of molecular pathways in the development of
different histological types of epithelial ovarian tumors.
He served as the principle investigators on multiple NIH
funded projects. His current research focuses on roles of
stromal cells in the initiation and progression of epithelial
ovarian tumors.
Sergei Orlovb

Dr. Orlov is professor of Medicine at University of Montreal,
Canada and professor of Biophysics at Moscow State University,
Russia. He also serves as Head of Laboratory of Pathophysiology
of Ion Transport Disorders at University of Montreal Hospital
Research Centre and a Head of Laboratory of Physical Chemistry
of Biomembranes, Faculty of Biology, Moscow State University.
His research is focus on the mechanism of ion transport
across plasma membrane and its role in cell volume regulation,
proliferation and death.
Masaomi Nangaku

Masaomi Nangaku, male, nephrologist, graduated from the
University of Tokyo School of Medicine in 1988. He worked
for the division of nephrology and endocrinology, the University
of Tokyo School of Medicine since. He worked at University
of Washington Medical Center, Seattle, U.S.A. as a visiting
scientist from 1994 to 1996 and served as a visiting professor
at University of Florida, Gainesville, U.S.A. in 2005. He
has been working on immune mediated glomerular and tubular
epithelial injury, and chronic hypoxia resulting in renal
tubular epithelial and interstitial injury as a final common
pathway t o end stage renal disease. He got the Young Investigator
Award of the Japanese Society of Nephrology in 2002, has
published more than 140 papers, and gave 20 invited talks
at international scientific meetings. He has also been a
member of Scientific Program Committee of World Congress
of Nephrology since 2005. His past and current editorial
responsibilities include Journal of the American Society
of Nephrology, Chinese Medical Journal, Nephrology Dialysis
and Transplantation, Nephron Experimental Nephrology, Clinical
and Experimental Nephrology, and Recent Patent Reviews on
Cardiovascular Drug Discovery.
Will Minuth

Dr. Will Minuth is a professor of Anatomy at the University
of Regensburg in Germany. He is teaching medical students
in Gross Anatomy, Histology and Neuroanatomy. The research
interest is related to the field of renal epithelial barrier
function including the action of steroidal hormones. The
driving force in his experimental work is the unsolved question,
if stem/progenitor cells can be applied in future to treat
acute or chronic renal failure. For that reason the actual
research of Dr. Minuth is focusing to renal stem/progenitor
cells developing into a functional epithelium under the
tubulogenic action of aldosterone. Sophisticated perfusion
culture including an artificial interstitium plays an essential
role in this hot spot of research.
Fátima Martel

Dr. Martel is a full professor of Medicine at Porto University.
She has been working on the transmembranar transport of
organic compounds (organic cations, folate, thiamine, glucose,
serotonin, butyrate, MPP+)
at the epithelial level. Most of her work has been conducted
at the intestinal and placental level, but transport at
other epithelia (blood-brain barrier, liver) have also been
performed. Her current research focuses on potential interaction
of drugs and epithelial transport of organic compounds,
on the effect of some particular pathologies on the transport
characteristics, and on the relation between transport of
a substance and its biological activity.
Mustafa F. Lokhandwala

Dr. Lokhandwala received his Ph.D. Degree from the University
of Houston and was appointed Assistant Professor of Pharmacology
in the College of Pharmacy at University of Houston. He
subsequently was promoted to Associate Professor and Professor
at the same institution. Dr. Lokhandwala also served as
Chair of the Department of Pharmacology from 1980-1991 and
Dean of the College of Pharmacy from 1991-2002. He currently
serves as Executive Vice-Dean for Research and Professor
of Pharmacology in the College of Pharmacy.
He is studying the mechanisms by which oxidative stress
causes renal dopamine receptor G-protein uncoupling in hypertension,
aging and diabetes and examining approaches to reverse and/or
prevent these changes in order to restore receptor G-protein
coupling and drug responsiveness leading to the maintenance
of sodium homeostasis and blood pressure.
He serves as Editor-in-Chief of the journal Clinical
and Experimental Hypertension and serves on editorial
boards of several journals, and has been a recipient of
several awards. He has published over 200 scientific papers
and his research is funded by the National Institutes of
Health.
Emiko Mizoguchi

Dr. Mizoguchi is an Assistant Professor of Medicine at Harvard
Medical School, and Assistant Immunologist, Gastrointestinal
Unit at Massachusetts General Hospital. She also serves
as a center investigator at an NIH funded Center for the
Study of Inflammatory Disease, one of twelve centers in
the United States that serve to support and coordinate research
among the laboratories within the Harvard Medical School
Community. Dr. Mizoguchi’s major research interest
is to identify the biological function of colonic epithelial
cells under normal and inflammatory conditions. She serves
as the Principal Investigator at Massachusetts General Hospital,
advisor of animal models of colitis and a member of scientific
advisory committee for pharmaceutical companies and research
institutes in the United States. Her current research focuses
on the functional role of tumor necrosis factor receptors
type-I and type-II in innate and acquired immune responses
and host-microbial interaction via mammalian chitinases
(e.g., chitinase 3-like-1/YKL-40) under inflammatory conditions.
Jean-François Beaulieu

Jean-François Beaulieu is a professor of Cell Biology
and the director of the Department of Anatomy & Cell
Biology at the Université de Sherbrooke. He holds
the Canada Research Chair in Intestinal Physiopathology.
He is also the leader of the Canadian Institutes of Health
Research Team on the Digestive Epithelium. Professor Beaulieu
has been working on the mechanisms that regulate gene expression
in the human epithelial cells of the developing gut and
adult intestine under normal and pathological conditions
(chronic inflammation, colorectal cancer, etc.). He has
contributed to the characterization and/or establishment
of several human intestinal epithelial cell models. His
current research focuses on epithelial cell-extracellular
matrix interactions in the intestine and the roles that
these macromolecules exert through specific membrane receptors
on the regulation of epithelial cell functions.
Suzana B. Veríssimo
de Mello

Dr. Suzana Beatriz Veríssimo de Mello, biologist
born in São Paulo, SP, Brazil is Associate professor
at Rheumatology Division of Internal Medicine
Department of Medical School, University of São Paulo,
Brazil. Dr. Mello has been working on the participation
of free radicals in the articular damage particularly with
synovial fluids of arthritic patient and with animal models.
Her current research focuses on synovial fluid of children
with juvenile rheumatoid arthritis and evaluating H2S production.
Actually they are also studying the leukocyte function (chemotaxis
and superoxide formation) in cells collected from Behcet
syndrome patients, as well as its correlation with CD14
and TLr, as well as the influence of LTA in this process.
Klaus Pantel
Prof. Pantel (M.D./Ph.D.) graduated in 1986 from Cologne
University in Germany and completed his thesis on mathematical
modelling of hematopoiesis in 1987. Prof. Pantel is currently
the Chairman of the Institute of Tumour Biology at the University
Medical Center Hamburg-Eppendorf (UKE), University of Hamburg,
Germany. He is Deputy Director of the Center of Experimental
Medicine at UKE that comprises 15 biomedical institutes
with access to patient samples through much clinical collaboration.
Prof. Pantel is on the Editorial Board of several international
cancer journals and coordinates the Consortium “Disseminated
Malignancies DISMAL” funded by the European Commission.
Over the past 15 years, he has organized 5 international
symposia on minimal residual cancer in Europe/USA, received
several awards and published more than 150 original papers
on the detection, characterization and clinical relevance
of micrometastatic disease.
Edward A. Ratovitski

Dr. Ratovitski is an associate professor of dermatology,
otolaryngology/head and neck surgery, oncology and pharmacology/molecular
sciences at the Johns Hopkins University School of Medicine.
He serves as an Associate Director of Head and Neck Cancer
Research Division. Dr. Ratovitski has been working on the
role of protein-protein interactions in cancer, epithelial/mesenchymal
transition, and epithelial developmental disorders. His
current research focuses on p63 function in epithelial cancers
and developmental disorders that carry p63 mutations, and
on search of potential agents
(inhibitory RNA, small inhibitory molecules) that would
affect p63 pathological manifestations at the RNA processing
level.
Fernando Navarro-Garcia

Dr. Navarro-Garcia is a Professor and Chairman of Cell Biology
Department at the Center for Research and Advance Studies
of National Polytechnic Institute (CINVESTAV-IPN) Mexico.
He is member of the Mexican Academy of Science and the National
System of Researchers and Advisor at the Academic Consulting
Board for CINVESTAV-IPN. He is also reviewer of scientific
proposals for National Council of Science and Technology
(CONACYT), Mexico and Science and Technology Fund (FONCYT),
Argentina. Dr. Navarro-Garcia has been working on the roles
of gut epithelial barrier function in bacterial and protozoa
infections (pathogenesis and mucosal immunity). He is a
specialist in interaction epithelial cell-enteropathogen,
with emphasis in epithelial membrane receptors, cytoskeleton,
intracellular trafficking of bacterial effectors, mucosal
antibodies, cytokines and cells from the immune system.
Weihong Pan

Dr. Pan is a professor in Neuroscience in Pennington Biomedical
Research Center, Louisiana State University System. She
is the associate editor for the journal Peptides, and editorial
board member for Current Pharmaceutical Design; Clinical
Medicine: Endocrinology and Diabetes; and Journal of Epithelial
Biology & Pharmacology. She is also a staff neurologist
at the Ochsner Clinic.
Dr. Pan's research focuses on the transport of peptides
and cytokines across the blood-brain barrier. Her area of
expertise includes endothelial trafficking, neuroinflammation,
neurotrauma, hypoxia, and CNS drug delivery. Dr. Pan serves
as a reviewer for various NIH study sections and over 40
international journals. She is one of the most productive
researchers in the blood-brain barrier field.
John P. Lydon

Dr. John P. Lydon is an associate professor at the department
of Molecular and Cellular Biology, Baylor College of Medicine,
Houston, Texas. Dr. Lydon’s research focuses on the
delineation of normal and abnormal cellular and molecular
mechanisms that underlie mammary and uterine epithelial
responses to steroid hormone exposure. Using state-of-the-art
mouse genetics, Dr. Lydon’s group has been instrumental
in dissecting progesterone receptor and coregulator control
of mammary and endometrial epithelial morphogenesis and
tumorigenesis. Apart from an academic educator and researcher,
Dr. Lydon serves on the editorial board of Endocrinology
and is an active reviewer for federal and private research
grant funding authorities.
Jacques Eduardo Nor

Dr. Nör is a Professor of Dentistry and Professor of
Biomedical Engineering at the University of Michigan. He
also serves as a member of the Developmental Therapeutics
study section at the NIH. Dr. Nör has been working
on head and neck tumor angiogenesis. He served as the principle
investigator for NIH grants and is in the editorial board
of several journals. His current research focuses on the
crosstalks between endothelial cells and squamous cell carcinoma
cells in head and neck cancer.
Jing-Lin Xia

Dr. Xia is a professor of Hepatic Oncology at Zhongshan
Hospital, Fudan University. Dr Xia has been working on roles
of HGF ameliorates hepatic biliary fibrosis in part by blocking
bile duct epithelial to mesenchymal transition (EMT). His
current research focuses on study of tumor angiogenesis
and anti-angiogenesis therapy. He also focuses on study
the value of TACE on liver cancer.
Keith R. McCrae
Dr. Keith McCrae is a Professor of Medicine and Pathology
at Case Western Reserve University School of Medicine. His
areas of interest include endothelial cell biology and angiogenesis,
as well as vascular inflammatory disorders, thrombosis and
hemostasis, and platelet disorders. He has served on several
NIH study sections, and is also a member of the editorial
boards of BLOOD and Thrombosis Research. He is also served
on advisory boards for organizations developing new thrombopoietic
agents and therapies for rare bleeding disorders. Dr McCrae
also cares for patients with a variety of hematologic diseases,
particularly thrombocytopenias, bleeding and clotting disorders.
Friedrich Paulsen

Dr. Paulsen is a professor of Anatomy at Martin Luther University
Halle-Wittenberg, member of the faculty council, corresponding
member of the Anatomical Society of Great Britain and Ireland,
honorary member of the Romanian Anatomical Society and secretary
of the German Anatomical Society. He is Editor-in-Chief
of the Annals of Anatomy and serves as chairmen of a professional
development center for Clinical Anatomy at MLU Halle. Dr.
Paulsen first worked as medical doctor in otorhinolaryngology
and then became anatomist. He has been studying already
at Christian Albrecht University of Kiel on roles of peptides
and proteins in innate immunity at the ocular surface and
lacrimal apparatus, articular joints and upper aerodigestive
tract including the larynx, corneal wound healing, dry eye
syndrome, corneal and conjunctival epithelial cells in pathogenesis
of inflammation, organ dysfunction and stem cells. He served
as the principle scientist and global advisor of scientific
advisory boards for national and international research
organizations and pharmaceutical companies. His current
research focuses on roles of mucins, antimicrobial peptides,
TFF peptides and surfactant proteins in development of organ
dysfunction and potential interaction between drugs and
epithelial cells.
Harshad A. Navsaria
Harshad A. Navsaria a Professor in Cell and Tissue Engineering
at the Centre for Cutaneous Research, Institute of Cell
and Molecular Science, Barts and London School of Medicine
and Dentistry, Queen Mary, University of London. He has
been working in the field of keratinocyte biology and tissue
engineering for the past 21 years.
Prof Navsaria is a member of the European Tissue Culture
Society, founder member of the European Tissue Engineering
Society, the British Burns Association, the British Society
of Investigative Dermatology, the European Society of Dermatological
Research, the European Tissue Repair Society, and the Tissue
Engineering Society (USA). He has served as a consultant
to Fidia Advanced Biopolymers (Italy), Steifel (UK) and
Convatec (UK & USA). Prof Navsaria also serves as a
consultant to St. Andrew’s Burns Centre, Broomfield
Hospital to direct and supervise research activities including
clinical application of tissue engineered skin for burn
patients. He has served as a board member on the scientific
advisory committee for Purdue University, USA on tissue
engineering.
Recently he was invited by the British Ambassador to Paraguay
and Dominican Republic to give a series of lectures on advances
in science for improved burn treatment and is assisting
with the establishment of a skin bank. Within the School
he is the Academic Dean and chairs the School Board.
Prof Navsaria publishes articles in peer reviewed journals
detailing his research in the field of keratinocyte biology
including reviews and book chapters.
Rama Mallampalli
Dr. Mallampalli is Professor of Medicine and Biochemistry
at the University of Iowa. He serves on several editorial
boards and peer review panels within the NIH. He is a member
of the American Society for Clinical Investigation and American
Society for Biochemistry and Molecular Biology. His laboratory
is supported by several granting mechanisms from the NIH
and Veteran’s Administration. His research program
investigates the biochemical and molecular basis for phosphatidylcholine
deficiencies observed in acute and chronic lung disorders
and focuses on type II alveolar lung epithelium. His current
research activities focus on the regulatory mechanisms for
lipid transporters and lipogenic enzymes involved in surfactant
phospholipid metabolism.
Laurent Misery
Prof. Laurent Misery is professor of Dermatology at the
University of Western Brittany in Brest. He is head of department
of dermatology and director of laboratory of skin neurobiology.
Pr Misery has worked on Langerhans cells and their precursors
and mucosal immunity against HIV. He serves as advisor for
pharmaceutical or cosmetological companies and research
organizations. His current research focuses on skin neurobiology,
itch and Merkel cells.
Rudolf Lucas
Having obtained his PhD in cellular and genetic biotechnology
at the university of Brussels, Belgium, Dr. Lucas became
chief assistant in the Department of Anesthesiology, Pharmacology
and Surgical Intensive Care at the University medical Center
in Geneva, Switzerland. Subsequently he was a senior visiting
scientist in the Dept. of Biological Chemistry at the Weizmann
Institute for Science in Israel and a vice chair in the
department of Biochemical Pharmacology at the university
of Konstanz, Germany. Dr. Lucas is currently an associate
professor of Pharmacology and Toxicology at the Vascular
Biology Center of the Medical College of Georgia in Augusta.
He was recently elected chair of the “Molecular pathology
and functional genomics” scientific group of the European
Respiratory Society. Over the past 15 years, Dr. Lucas has
been investigating the role of the pro-inflammatory cytokines
in ARDS and permeability edema. His current research focuses
on the regulation of alveolar epithelial sodium channels
by Tumor Necrosis Factor and has resulted in the identification
of a novel domain of the cytokine, i.e. the lectin-like
domain, which is spatially distinct from the receptor binding
sites, and which is implicated in the activation of pulmonary
edema reabsorption.
Baharia Mograbi
Baharia Mograbi has a permanent position as senior research
scientist (CR1) at INSERM since 2003. She is scientific
advisor board for Nice hospital Biobank, pharmaceutical
companies, and research organizations. During her graduate
work, she studied the expression of EGF family ligands by
activated macrophages. After obtaining her PhD, She joined
Giovanni Romeo Laboratory at Gaslini Institute in Genoa,
Italy to delineate the GDNF/Ret RTK survival-signalling
pathway. In the 2000s, B Mograbi and al. unravelled how
a gain-of-function mutation Ret mutation can be associated
with both cancer (multiple endocrine neoplasia) and a developmental
defect (Hirschsprung disease). Back to France at the faculty
of Medical School at Nice-Sophia Antipolis University, she
quickly moved on to explore the molecular control of the
autophagy pathway, an catabolic pathway involved in a growing
list of diseases ranging from neurodegenerative disease,
infections and cancers. In particular she focussed on the
deregulation of this tumour suppressor pathway by environmental
carcinogens and oncogenes, a field that still holds her
attention.
Claire M. Payne
Dr. Payne is a research professor in the Department of Cell
Biology & Anatomy at the University of Arizona, a member
of the Arizona Cancer Center, a visiting research scientist
at the Southern Arizona Veterans Affairs Health Care System
and President of Biomedical Diagnostics & Research,
Inc. in Tucson. Dr. Payne has published in the areas of
viral gastroenteritis, glomerulonephritis, neuroendocrine
cytochemistry, esophagitis, colitis, colon carcinogenesis,
field cancerization/field defects, ultrastructural diagnosis
of human disease and cell death mechanisms. Her current
research focuses on the induction of oxidative/nitrosative
stresses and genomic instability in colonic epithelial cells
by hydrophobic bile acids.
José M. López-Novoa
Dr. Lopez- Novoa is a Full Professor of Physiology at Faculty
of Medicine, University of Salamanca, Spain, and Director
of the Renal and Cardiovascular Physiopathology Unit, Institute
“Queen Sophie” for Renal Research since 1990.
Previously, he has been Associate Research Scientist in
the Nephrology department of Jimenez Diaz Foundation, in
Madrid, Spain, and as Professor of Research in the Spanish
High Council for Scientific Research (CSIC). Dr Lopez-Novoa
has been working on epithelial transport in the kidney in
hepatic cirrhosis and during acute renal failure. He serves
as member of the Scientific and Medical Board (SMAB) of
the International HHT Foundation, the Executive committee
of the Institute “Queen Sophie” for Renal Research.
He is a member of the Editorial Board of several Journals,
including Nephrology Dialysis and transplantation (the official
journal of the European Society of Nephrology), Nephrología
(the official journal of the Spanish Society of Nephrology),
and Journal of Physiology and Biochemistry. His current
research in the area of epithelial cells focuses on the
mechanisms of tubular epithelial cell necrosis in response
to drugs and heavy metals, as well s the mechanisms of prevention,
as well as the mechanisms of acute pancreatitis.
James Mullin
Dr. Jim Mullin is a Professor at the Lankenau Institute
for Medical Research and Director of Research in the Division
of Gastroenterology of Lankenau Hospital, Wynnewood, Pennsylvania.
After completing graduate study in physiology at the University
of Pennsylvania School of Medicine, he performed postdoctoral
work at the Dept. of Human Genetics, Yale University School
of Medicine, and the Wistar Institute at the University
of Pennsylvania. He is adjunct Professor of Biology at Saint
Joseph’s University in Philadelphia, currently serving
as the liaison for graduate studies in Biology between Lankenau
and Saint Joseph’s. He also serves on the Graduate
Medical Education Committee of Lankenau Hospital and has
recently been a member of the NIH/NCI study panel for Applications
of Emerging Technologies for Cancer Research. Dr. Mullin’s
research focuses on epithelial barrier function, alteration
of transepithelial permeability by pharmacological agents
and diseases, paracellular transport through the epithelial
tight junction, and regulation of tight junction permeability
by protein kinase C. Dr. Mullin holds a US Patent on the
screening for Barrett’s esophagus by transepithelial
leak, and is the author of several reviews on tight junction
permeability and its alteration in disease.
Sabrina Mattoli
Dr. Mattoli holds a Specialty Diploma in Pulmonary Medicine
and has spent more than 15 years in specialty practice.
She also has an extensive experience in lung molecular biology,
pharmacology and drug development, based on previous work
in academic research institutions and in the pharmaceutical
industry. As co-founder and Scientific Director of the Avail
Biomedical Research Institute (Basel, Switzerland), her
research interests in the last 9 years have focused on the
role of intrinsic defects of the airway epithelial barrier
in the pathogenesis of pulmonary diseases resulting from
the interaction between susceptibility genes and environmental
factors, and on the evaluation of the potential role of
bone marrow-derived progenitors in airway tissue repair.
Theodor Petrov
Dr. Petrov, MD, PHD is an Associate Professor at the Department
of Anatomy and Cell Biology, the School of Medicine, Wayne
State University in Detroit, Michigan. Previously he worked
at the School of Medicine, University of Alberta, Edmonton,
Alberta, Canada and at the Pasteur Institute in Paris, France.
During the past decade he has served as a reviewer for numerous
renowned scientific journals. He developed therapeutic interventions,
such as in vivo application of antisense oligonucleotides
which attenuate expression of genes in endothelial cells
(the cells that form the vascular wall). The protein products
of these genes participate in cascades of events that lead
to abnormal perfusion and cell injury. This is established
by functional magnetic resonance imaging (fMRI) which allows
assessment of brain perfusion in the entire brain. His current
interests are related to the expression of endothelial receptors
which may mediate intracellular events that are deleterious
to cell survival involving disturbed mitochondrial metabolism
and generation of free radicals.
Véronique Moulin
Dr. Moulin is adjunct professor at the surgery department
of the faculty of medicine at Laval University. She is researcher
at the LOEX at the Centre hospitalier affilié universitaire
de Québec. Her work is dedicated to the comprehension
of wound healing and fibrosis phenomena using several study
models such as tissue engineered skins and animal models.
Her most recent achievements comprise the production using
tissue engineering techniques of a reconstructed skin model
for wound healing studies, functional studies of wound dermal
cells, the myofibroblasts and evidence of the importance
of interactions between keratinocytes, the epithelial cells
of the skin, and dermal cells during fibrosis.
Heiko Mühl
Dr. Mühl is groupleader and principal investigator
at the pharmazentrum frankfurt, University Hospital
Johann Wolfgang Goethe-University Frankfurt am Main. The
biochemist /pharmacologist has been working on mechanisms
that initiate and control inflammatory processes with special
focus on the immunopharmacology of cytokine biology and
nitric oxide. Current research concentrates on the epithelial
cell compartment as active component of innate immunity.
Particularly, interactions between leukocytes and epithelial
cells are being investigated in the context of Th1/Th17
cytokine responses, inflammation, and carcinogenesis.
Hannes Lohi
Dr. Lohi is a professor of molecular genetics at the University
of Helsinki in the Departments of Medical Genetics and Basic
Veterinary Sciences. He is also a group leader in the Folkhälsan
Institute of Genetics. Dr. Lohi has been working with several
human genetic diseases and related genes. He was discovering
several new members in the SLC26 family of anion exchangers,
which have important epithelial transport functions in different
parts of the body. Several members of the gene family have
been associated with different type of genetic diseases
in human. Dr Lohi has also worked with genetic and functional
aspects of mismatch repair in colorectal cancer and has
several publications on human neurogenetics. His current
research focuses on canine inherited diseases as models
for human genetic diseases. He has established a large Dog
DNA bank in Finland and maps new disease in for many disease
phenotypes including several epithelial disorders of various
organs and cancers.
Ivan Robert Nabi
Dr. Nabi is a Professor in the Department of Cellular and
Physiological Sciences at the University of British Columbia.
He has worked in the fields of cancer metastasis, epithelial
polarity and protein trafficking. Research in his lab currently
focuses on the cell biology of cancer focusing on mechanisms
underlying motility and metastasis of epithelial-derived
cancer cells. Dr. Nabi works actively on raft-dependent
endocytosis, endoplasmic reticulum domains, cell surface
domain regulation of receptor activation and dynamics, and
the proteome and local signaling events that drive formation
of tumor cell protrusions.
Angela Panoskaltsis-Mortari
Dr. Panoskaltsis-Mortari received her PhD from the University
of Western Ontario. She was a post-doctoral fellow in the
Department of Pathology at the University of Alabama and
a post-doctoral research associate in the Department of
Pediatrics at the University of Minnesota. She joined the
University of Minnesota faculty in 1995.
Panoskaltsis-Mortari has board certification from the American
Board of Medical Laboratory Immunology. She is a member of
numerous immunology, pulmonary and hematology professional
societies, and the author of nearly 120 articles which have
appeared in such publications as Journal of Experimental
Medicine, Journal of Clinical Investigation, Blood,
Biology of Blood and Marrow Transplantation, American Journal
of Physiology (Lung, Cell. & Mol. Physiol.) and Journal
of Immunology.
G.J. Peters
Professor Godefridus (Frits) J. Peters is head of the Laboratory
of the department of Medical Oncology of the VU University
Medical Center (VUmc) in Amsterdam (the Netherlands). He studied
biology and chemistry at the University of Nijmegen, obtained
his master’s degree in biochemistry in 1977 and his
Ph.D. in 1982 on the relation between inborn errors and immunodeficiency
diseases. He did a post-doc at the Netherlands Cancer Institute
in Amsterdam, and subsequently at the Free University Hospital
in Amsterdam. In 1986 he received a senior research fellowship
of the Royal Netherlands Academy of Arts and Sciences, in
1989 he was appointed as head of the division of Biochemical
Pharmacology, in 1998 as head of the division of Pharmacology
and deputy-head of the laboratory and in 2003 as head of the
Laboratory of the Department of Medical Oncology. He was appointed
as associate-professor in 1992 and as full professor in 2003.
Venkat Keshamouni
Dr. Keshamouni is an Assistant Professor of Medicine at University
of Michigan, USA. Dr. Keshamouni's interests are investigating
mechanisms of metastasis and novel therapeutic approaches
for lung cancer. He is currently focused on investigating
Interactions between tumor cells, tumor associated macrophages
and fibroblasts in lung tumor Microenvironment, and Epithelial-mesenchymal
transitions, by utilizing cell culture, animal models and
systems biology approaches. Dr. Keshamouni serves on study
sections of various foundations that support cancer research,
and as a manuscript reviewer for a number of other international
journals. He is currently editing a book titled "Lung
Cancer Metastasis: Novel Biological Principles and Their Implications
for Clinical Practice".
Fiona McDonald
Dr Fiona McDonald is a Senior Lecturer in the Department of
Physiology at the University of Otago in New Zealand. Her
research is focused on the epithelial sodium channel and its
interactions with other proteins. This has lead to research
in the control of ion channels by trafficking and the ubiquitin
pathway.
Bertil Lindmark
In his role as Global Vice President, Clinical in AstraZeneca
for the Respiratory & Inflammation Therapy Area Bertil
Lindmark is responsible for Clinical and Strategic support
to the therapy area, management of clinical programmes in
drug development, driving in-licensing disease area, and clinical
strategies.
Bertil Lindmark joined Astra in 1991 after 10 years in Clinical
Medicine. His research interests are molecular epidemiology
with focus on protease inhibitors. Bertil Lindmark has held
a number of management positions in Astra and in AstraZeneca
including Drug Safety, Clinical Science, and Therapy Area
Medical Director.
Y. Marunaka
Dr. Marunaka is a professor and chairperson, Departments of
Molecular Cell Physiology and Respiratory Medicine, Graduate
School of Medical Science, Kyoto Prefectural University of
Medicine, Japan. He also serves as Director, Center for Medical
Education and Research at the university. He is an Editor,
Journal of Physiological Sciences, and an Editorial Board
Member, Evidence-based Complementary and Alternative Medicine.
He was also an Editorial Review Board Member, American Journal
of Physiology Renal Physiology, and a member, Program Committee
Member, American Thoracic Society. He obtained an MD degree
(1979) and a PhD degree (1985) from Kyoto Prefectural University
of Medicine. He was an Instructor, Department of Physiology,
Shiga University Medical Science, a Research Associate, Department
of Physiology and Biophysics, University of Texas Medical
Branch at Galveston, an Assistant Professor, Department of
Physiology, Emory University School of Medicine, and an Associate
Professor, Department of Pediatrics, University of Toronto
and a Senior Scientist, Research Institute, Hospital for Sick
Children (Toronto). He is a chairperson, the 86th Annual Meeting,
Physiological Society of Japan held in Kyoto (2009). His current
research focuses on regulation of epithelial ion transport,
epithelial cell growth, and roles of chloride ions in cell
function including cell growth, neurite elongation etc.