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Recent Patents
on Cardiovascular Drug Discovery
ISSN: 1574-8901 - Volume 4, 3 Issues, 2009
Instructions for Authors
Journal Scope:
Recent Patents on Cardiovascular Drug Discovery
publishes review articles on recent patents in the field of
cardiovascular drug discovery e.g. on novel bioactive compounds,
analogs & targets. A selection of important and recent
annotated patents on cardiovascular drug discovery is also
included in the journal. The journal is essential reading
for all researchers involved in cardiovascular drug design
and discovery.
Online Manuscript Submission: Manuscripts must only
be submitted online to the Bentham Science Editorial Office.
It is preferable that authors first send an abstract to the
editor, prior to submitting the full manuscript. The submitted
abstract should outline the intended contents and coverage
of the article. Abstracts may be sent either by e-mail to
the editorial office at
patents@bentham.org or alternatively by the Internet at
www.bentham.org/onlAbsSub.htm
A successful electronic submission of a manuscript will be
followed by a system-generated acknowledgement to the principal/corresponding
author within 72 hours of the dispatch of the manuscript.
Any queries therein should be addressed to mahmood@bentham.org
and copied to Jalil@bentham.org
After approval of your abstract by the editor, you may submit
your fully copyedited manuscript either by e-mail (file size
restricted) or by online submission. In case of urgency, the
entire manuscript may be sent.
Short review manuscripts may be submitted as an email attachment
(maximum file size 512 KB) to the editorial office at patents@bentham.org.
Manuscripts should be submitted via our online manuscript
submission service available at www.bentham-mps.org
or by FTP submission at www.bentham-ftp.org.
For all online submissions, please provide your complete manuscript
in the form of a single zipped folder containing soft copies
of all the material (main text in MS word format, figures
/ illustrations, scanned photographs, tables, chemical structures
drawn in ChemDraw) as separate files, while a PDF version
of the entire manuscript must also be included with all the
figures / illustrations / tables / chemical structures etc.
embedded in the text exactly in the manner as they should
appear in print.
Authors are required to proofread the PDF version of their
manuscript before submission. After a maximum of three proofs,
the manuscript will be published as it is. The Publishers
will not be held responsible for errors in this regard.
Manuscript Length: Page lengths can vary for mini-reviews
of up to 12 journal pages and for longer reviews up to 30
journal pages. A printed journal page is ca. 900 words (excluding
diagrams and figures).
Manuscript Organization: The manuscript should be divided
as: Title page, abstract and the main text. The text may be
subdivided further according to the areas to be discussed.
The acknowledgements (if any) and reference sections must
then follow.
Conflict of Interest: Financial contributions
to the work being reported should be clearly acknowledged,
as should any potential conflict of interest. No patents should
be cited by authors which are in various stages of legel litigation.
Acknowledgements: Please acknowledge anyone
(individual/company/institution) who has contributed to the
study by making substantial contributions to conception, design,
acquisition of data, or analysis and interpretation of data,
or who was involved in drafting the manuscript or revising
it critically for important intellectual content. Please list
the source(s) of funding for the study, for each author, and
for the manuscript preparation in the acknowledgements section.
This journal complies with the International Committee of
Medical Journal Editors' Uniform Requirements for Manuscripts
Submitted to Biomedical Journals www.icmje.org <http://www.icmje.org>
and the FDA's Good Reprint Practices for the Distribution
of Medical Journal Articles and Medical or Scientific Reference
Publications on Unapproved New Uses of Approved Drugs and
Approved or Cleared Medical Devices http://www.fda.gov/oc/op/goodreprint.html
Patent Review Coverage: Authors should review
the most recent and important patents based on the topic covered.
Coverage of novel bioactive compounds, analogs and targets
should be emphasized, including the significance of reported
patents.
Current & Future Developments: The review article
should conclude with a short section called “Current
& Future Developments”. The author(s) will give their
opinion on the current and future important developments on
the topic discussed in their article.
Title Page: The first page should contain the title,
the author's full names, institutional affiliations and location,
with an asterisk in front of the name of the principal author.
The corresponding author should be designated and their full
address, business telephone, fax number and the e-mail address
must be stated to receive correspondence and galley proofs.
Abstract: The abstract should not exceed 200 words
and should summarize the essential features of the review
article and include information regarding patents cited in
the review articles.
Keywords: Authors must supply up to fifteen keywords
along with their manuscript.
Short Running Title: Authors must provide
a short running title of their manuscript on submission.
Text: The main text should begin on a separate page
and it may be subdivided into separate sections. The reference
numbers should be given in square brackets in the text. Acknowledgements
should be kept to a minimum.
Tables:
- Data tables should
be submitted in Microsoft Excel or in Microsoft Word table
format.
- Each table should include
a title/caption explaining what the table shows. Detailed legends may then follow.
-
Tables should be given on separate pages with indications on the left hand margin
to the text, as to the appropriate placement of the tables.
-
Tables should not contain vertical rules.
-
Columns and rows of data should be made visibly distinct by ensuring the borders
of each cell display as black lines.
-
Tables should be numbered consecutively in order of their citation in the body
of the text, with Arabic numerals.
-
If a reference is cited in both the table and text, insert a lettered footnote
in the table to refer to the numbered reference in the text.
-
Tabular data provided as additional files can be submitted as an Excel spreadsheet.
Figures / Illustrations: All authors must strictly
follow the guidelines below for preparing illustrations for
publication in Recent Patents on Cardiovascular Drug
Discovery. If the figures are found to be sub-standard,
then the manuscripts will be rejected/ and the authors offered
the option of figure improvement professionally by Bentham
Publishing Services. The costs for such improvement will be
charged to the authors.
Editorial
Requirements:
The quality of the illustrations printed in the journal largely
depends on the quality of the figures/illustration provided
by the author. The acceptance of a manuscript for publication
is subject to the figures being up to the highest standards
in terms of clarity and resolution. In case the figures supplied
are not up to the standards required, then the manuscripts
will be rejected, and the authors given the option to either
return the manuscripts within one week with appropriate drawings/figures
or they may opt to have these professionally prepared through
the paid professional service available from Bentham Publishing
Services.
- Submit the original artwork or a photographic
print of the original for publication.
- Do not submit photocopies. (Hardcopy submission
requirement).
- Illustrations should be provided as separate
files, not embedded in the text. (Hardcopy submission requirement).
- Remove all color from graphics except for
those illustrations (Greyscale), which are intended to be
printed in color.
- Good quality of hardcopy originals are a
requirement.
- Figures should be referred to as “Fig.
(1)”, “Fig. (2)” etc. in the
text with figure numbers in bold within round bracket.
- Revised manuscripts should contain a complete
set of artwork and photographs.
Technical
Details:
- Figures should be provided on high quality,
white, smooth opaque paper. (Hardcopy requirement).
Format
& Resolution:
- The following file formats can be accepted.
(Preference in order of appearance): PDF, TIFF, JPEG, GIF.
- Illustrations
must fit a single or double column format on the journal page, according to the
following guideline below:
|
HEIGHT | WIDTH |
SINGLE COLUMN |
24 cm (max) |
8.5 cm (max) | DOUBLE
COLUMN | 24
cm (max) | 18
cm (max) |
- Whenever possible, submit
graphics that do not have to be reduced to fit the standard figure size.
-
Use the best resolution available (hardcopy submission requirement). For online
submission the maximum resolution is 300 dpi.
- Avoid textures
and shadings giving a three-dimensional effect to the illustration.
-
Symbols and lettering in the illustration should be of similar size.
-
Smaller lettering is used.
- Font: Times New Roman or Helvetica is preferable.
Font size: 10pt (maximum).
- Line drawings should
have clear and sharp lines and should be of uniform density. Moreover, lines should
be continuous without any breaks.
- Do not use lines thinner
than 1 point.
Color Figures / Illustrations:
-
The cost for the first published page
of color figure(s) is USD 850; the second additional page
will be for USD 621, and each subsequent page for USD
420.
- Color figures should be supplied in CMYK not
RGB colors.
Photographs: Submit high-contrast prints that are
of single- or double-column width so that they will not have
to be reduced when printed. Negatives are not acceptable.
However, in case of hardcopy submission, color illustrations
and plates can be published from 35 mm color slides.
Chemical Structures: Chemical structures must be prepared
according to the guidelines below.
Structures should be prepared using a suitable drawing program
e.g. ChemDraw and provided as separate file, submitted both
on disk and in printed formats.
Numbers in bold should identify all chemical structure. If
a name is also used to describe the compound, the associated
number in bold should be in parenthesis, e.g. “compound
(1)”.
Structure Drawing Preferences:
[As according to the ACS style sheet]
Drawing Settings:
Chain angle 120°
Bond spacing 18% of width
Fixed length 14.4 pt
(0.500cm, 0.2in)
Bold width
2.0 pt (0.071cm, 0.0278in)
Line width
0.6 pt (0.021cm, 0.0084in)
Margin width 1.6 pt
(0.096cm)
Harsh spacing 2.5 pt (0.088cm, 0.0347in)
Text settings:
Font Times
New Roman / Helvetica
Size 10pt
Under the Preference Choose:
Units
points
Tolerances 3
pixels
Under Page Setup Use:
Paper US
letter
Scale
100%
Symbols and Units:
Greek symbols and special characters often undergo formatting
changes and get corrupted or lost during preparation of a
manuscript for publication. To ensure that all special characters
used are embedded in the text, these special characters should
be inserted as a symbol but should not be a result of any
format styling (Symbol font face) otherwise they
will be lost during conversion to PDF/XML.2
Authors are encouraged to consult reporting guidelines. These
guidelines provide a set of recommendations comprising a list
of items relevant to their specific research design.
Only ISO symbols, written in italic,
should be used for the various parameters. All kinds of measurements
should be reported only in International System of Units (SI).
SI units should always be written in Roman and separated from
the numerical value by a space (whatever the language). The
μ
in μg
or μm
should be in Roman. The symbol for litre is L and that for
minute is min. For temperatures, please use any one of °C,
°F
or K in the entire manuscript. As the Angström (1#A =
10-10 m) is not an SI unit,
it should be replaced by the nanometre (1 nm = 10-9
m) or by the picometer (1pm = 10-12
m): 1#A = 0.1 nm = 100 pm. Multiple units should be written
with negative superscripts (for example, 25 mgμL-1
μs-1).
The list of notations should appear just before the first
paragraph of full text.
A list of symbols and units should be provided if used extensively
throughout the text.
List of Abbreviations: If abbreviations are
used in the text either they should be defined in the text
where first used, or a list of abbreviations can be provided.
References: References
should be numbered sequentially [in square brackets] in the
text and listed in the same numerical order in the reference
section.
All references must be complete and accurate. Online citations
should include the date of access. Journal titles should conform
to the present Index Medicus abbreviations. It is necessary
to list all authors if the total number of authors is 6 or
less and for more than 6 authors use 3 authors and then et
al. References should be listed in the following Vancouver
Style.
Typical Paper Reference:
Boehm M, Nabel EG. Angiotensin-converting enzyme 2
- A new cardiac regulator. N Engl J Med 2002; 347: 1795-1797.
Typical Chapter Reference:
Yeh DC, Rocco T In: David EG, Armen HT, Ehrin JA, April
WA, Eds, Integrative Cardiovascular Pharmacology. Philadelphia,
Lippincott Williams & Wilkins. 2005: 375-383.
Meeting Abstract:
Hoffman, BJ. Metabolism: Amino acid transporters as
targets for therapeutic intervention. American Chemical
Society - 228th National Meeting, Philadelphia, USA (2004).
Patent References:
As a service, the Publishers will provide each author
a certain number of relevant patents to assist them in writing
their article. All patent application references will be provided
by the author and will be published as it is.
Patent Reference Style:
All inventor's names of the cited patents must be stated
e.g.
Chesnut, J.D., Carrino, J., Leong, L., Madden, K., Gleeson,
M.A.G., Fan, J., Brasch, M.A., Cheo, D., Hartley, J.L.,Byrd,
D.R.N.,Temple, G.F.: US20077198924 (2007).
Citation of the patents will be according to the international
convention as follows:
WO patents: 1978-2003
Yue, S., Johnson, I., Haugland, R.: WO9306482 (1993).
Li, Q., Guo, Z.Y., Kane, T., Liu, Z.: WO03033743 (2003).
WO patents: 2004 onwards
Abad, A., Dong, H., Lo, S.B., McCutchen, B.F., Shi, X.: WO2008011565
(2008).
US Patent Applications: 2001 onwards
Adang, A.E.P., Van Boeckel, C.A.A., Peters, J.A.M.,
Grootenhuis, P.D.J.: US20010007764A1 (2001).
Stefanadis, C., Kipshidze, N.: US20090030494A1 (2009).
Issued / Granted Patents:
Hultmark, D., Steiner, H., Rasmuson, T., Boman, H.G.:
US4355104 (1982).
Garbe, C., Schittek, B.: US7348409 (2008).
EP patents:
Sutherland, J.W., Patterson, D. R.: EP684316 (1995).
Une, K., Saito, J., Hayashi, T.: EP1780289 (2007).
SUPPORTIVE/SUPPLEMENTARY MATERIAL: We do
encourage to append supportive material, for example a PowerPoint
file containing a talk about the study, a PowerPoint file
containing additional screenshots, a Word, RTF, or PDF document
showing the original instrument(s) used, a video, or the original
data (SAS/SPSS files, Excel files, Access Db files etc.) provided
it is inevitable or endorsed by the journal's Editor.
Published/reproduced material should not be included unless
you have obtained written permission from the copyright holder,
which must be forwarded to the Editorial Office in case of
acceptance of your article for publication.
Supportive/Supplementary material intended for publication
must be numbered and referred to in the manuscript but should
not be a part of the submitted paper. In-text citations as
well as a section with the heading "Supportive/Supplementary
Material" before the "References" section should
be provided. Here, list all Supportive/Supplementary Material
and include a brief caption line for each file describing
its contents.
Any additional files will be linked into the final published
article in the form supplied by the author, but will not be
displayed within the paper. They will be made available in
exactly the same form as originally provided only on our Web
site. Please also make sure that each additional file is a
single table, figure or movie (please do not upload linked
worksheets or PDF files larger than one sheet). Supportive/
Supplementary material must be provided in a single zipped
file not larger than 4 MB.
Authors must clearly indicate if these files are not for publication
but meant for the reviewers'/editors' perusal only.
Page Charges: No page charges will be levied
to authors.
Language Editing: Manuscripts submitted containing
many English typographical errors will not be published. Authors
from non-English language countries are advised to use the
services of our professional language editing department prior
to submitting their manuscript to the Journal. Please contact
Bentham Publishing Services www.benthampublishingservices.com
for a language editing quote at e-mail: info@benthampublishingservices.com
stating the total number of words of the article to be edited.
Proofs: Authors are sent page proofs. To
avoid delays in publication, proofs should be checked immediately
for typographical errors and returned within 48 hours.
Authors will be charged for excessive changes made at the
page proof stage.
Reprints: Each first-named (corresponding)
author will receive electronically a certain number of free
reprints. Reprints may be ordered from the Publisher prior
to publication of the article. First named authors may also
order a personal print and online subscription of the journal
at 50% off the normal subscription rate by contacting the
subscription department at e-mail: subscriptions@bentham.org
Bentham Open Access: Accepted articles can
be published online for free open access for all to view.
Open access publishing provides the maximum dissemination
of the article to the largest audience. Authors must pay for
this service. All corresponding authors will be asked to indicate
whether or not they wish to pay to have their paper made freely
available on publication. If authors do not select the Open
Access option, then their article will be published with standard
subscription-based access at no charge.
Bentham Science offers authors the choice of open access publication
of their articles at a fee of USD 2,800 per published article
which allows indefinite free-to-view online publication with
Bentham Science.
Alternatively, authors may choose to publish their article
with Bentham Science at a reduced fee for a limited open access
period. Bentham Science is the first and only publisher to
offer authors the choice at a reduced open access fee to have
their article published for a limited open access period.
For open access publication for a period of either twelve
months or two months (limited open access option) the per
article fee is USD 1,400 or USD 700, respectively.
For more information please contact us at e-mail: openaccess@bentham.org
Reviewing and Promptness of Publication:
All papers submitted for publication will be immediately subjected
to editorial scrutiny, usually in consultation with members
of the Editorial Advisory Board. Every effort will be made
to assess the papers quickly. The papers will be typeset and
the proofs dispatched to the authors normally within 4 weeks
of their acceptance.
Copyright: It is a condition of publication
that manuscripts submitted to this journal have not been published
and will not be simultaneously submitted or published elsewhere.
Plagiarism is strictly forbidden, and by submitting the article
for publication the authors agree that the publishers have
the legal right to take appropriate action against the authors,
if plagiarism is discovered. By submitting a manuscript the
authors agree that the copyright of their article is transferred
to the publishers if and when the article is accepted for
publication.
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